C-Type lectin receptors (CLRs) constitute a family of pattern recognition receptors expressed primarily on myeloid cells that detect carbohydrate moieties on fungal cell walls. Through recognition of ...

The innate immune system, located in the skin and the mucous membranes is a highly complex physical and chemical barrier providing a first line defense ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

The main function of CRISPR-Cas systems is to defend bacteria against various threats, including viruses called bacteriophages. Researchers have continued to study all varieties of CRISPR-Cas systems ...

Low-input Promoter Capture Hi-C helped connect disease-associated variants to target genes in rare innate lymphoid cells.

Cancer immunotherapy, which primes the body's immune system to fight off tumors, has historically focused on harnessing T cells' natural ability to recognize and attack cancer cells. While this ...

Our immune system is divided into two main branches: innate and adaptive. Innate immune cells act as a first line of defense, quickly responding to invaders, while adaptive immune cells take a longer ...

Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...