Spatial transcriptomics is transforming how scientists see biology—literally—by mapping gene activity in its original location inside tissues. From decoding tumor architecture to charting entire ...

Glioblastoma (GBM) is an aggressive type of brain cancer that is known to be very difficult to treat. One reason why this ...

Transcriptomic phenotyping offers mechanistic insight into adipocyte biology and metabolic disease. A signature of adipocyte ...

Scientists have produced the first comprehensive map of olfactory receptors in the mouse nose, overturning the belief that they were randomly arranged. Using advanced single-cell sequencing and ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...